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cow-2022-18

CASE OF THE WEEK

Editor: Mahmut Akgul (akgulm@amc.edu)

2022-18/May 2

Contributors: Andrea de Oliveira Cruz, Paulo Athanazio, Daniel Athanazio

A male patient in his 80s with a 1.5 cm polypoid and ulcerated lesion in scrotal skin.

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Quiz

a) Fibroepithelioma of Pinkus
b) “Giant vascular” spiradenoma
c) Squamous cell carcinoma
d) Epithelioid hemangioendothelioma
e) Pyogenic granuloma

1. b

1. “Giant vascular” spiradenoma
Spiradenoma (eccrinespiradenoma) is a benign adnexal tumor with eccrine differentiation, that is probably derived from the secretory coil of sweat glands. Giant vascular spiradenoma is a rare variant characterized by marked vascularity and large size.(1)There are 14 reports to date in English literature and one previous case located in scrotal skin.(2) The size of reported tumors ranged from 2cm to 7cm diameter. Ulceration and associated epidermal hyperplasia as well as marked vascular proliferation may yield a broad spectrum of other diagnostic considerations. The present case was a small lesion (1.5 cm) with morphology very reminiscent of these larger tumors.

1. Cotton DW, Slater DN, Rooney N, Goepel JR, Mills PM. Giant vascular eccrine spiradenomas: a report of two cases with histology, immunohistology and electron microscopy. Histopathology. 1986 Oct;10(10):1093-9.

2. Li Z, Li G, Jiang X, Fu X. Giantvascular eccrine spiradenoma: the first case in the scrotum and review of the literature author. Diagn Pathol. 2021 Apr 30;16(1):37.

Andrea de Oliveira Cruz
Imagepat, Laboratory of Pathology
Salvador, Bahia, Brazil

Paulo Athanazio
Imagepat, Laboratory of Pathology
Salvador, Bahia, Brazil

Daniel Athanazio
Imagepat, Laboratory of Pathology, Federal University of Bahia / Hospital Universitário Professor Edgard Santos,
Salvador, Bahia, Brazil

Scrotum

Scrotum; Spiradenoma; Sweat Glands