Current Case of the Week 2025
2025 – 4/Apr 21
22 y/o male with a self-palpated painless testicular mass, normal serum tumor markers, and an 11mm heterogeneous, hypoechoic, well-marginated vascular mass on US. Right orchiectomy showed a firm, white-tan, well-circumscribed, 1.2 cm lower-pole tumor abutting the tunica albuginea (H&E images 1-4). IHC was positive for β-catenin (image 5) and vimentin, but negative for CK-OSCAR, AE1/AE3, EMA, CK7, CK20, inhibin, calretinin, WT-1, Melan-A, PLAP, SALL4, AFP, CD117, CD30, GATA3, p63, desmin, ERG, NKX3.1, and Ki-67 (1%).
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22 y/o male with a self-palpated painless testicular mass, normal serum tumor markers, and an 11mm heterogeneous, hypoechoic, well-marginated vascular mass on US. Right orchiectomy showed a firm, white-tan, well-circumscribed, 1.2 cm lower-pole tumor abutting the tunica albuginea (H&E images 1-4). IHC was positive for β-catenin (image 5) and vimentin, but negative for CK-OSCAR, AE1/AE3, EMA, CK7, CK20, inhibin, calretinin, WT-1, Melan-A, PLAP, SALL4, AFP, CD117, CD30, GATA3, p63, desmin, ERG, NKX3.1, and Ki-67 (1%).
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2025 – 3/Mar 24
68-year-old male patient with unremarkable past medical history presents due to fullness in the left flank and weight loss. Computed Tomography showed an 11.5 cm solid and cystic mass suggestive of renal cell carcinoma. A radical nephrectomy with lymph node dissection was performed.
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68-year-old male patient with unremarkable past medical history presents due to fullness in the left flank and weight loss. Computed Tomography showed an 11.5 cm solid and cystic mass suggestive of renal cell carcinoma. A radical nephrectomy with lymph node dissection was performed.
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2025 – 2/Feb 24
A 52-year-old female had a clinical history of E. coli infections, leading to renal and retroperitoneal abscesses formation with spinal extension. She underwent a left radical nephrectomy. A circumscribed tan-red nodule (2.2 cm in greatest dimension) was seen grossly within the necrotic renal parenchyma.
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A 52-year-old female had a clinical history of E. coli infections, leading to renal and retroperitoneal abscesses formation with spinal extension. She underwent a left radical nephrectomy. A circumscribed tan-red nodule (2.2 cm in greatest dimension) was seen grossly within the necrotic renal parenchyma.
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2025 – 1/Jan 20
Case History: A 58-year-old female patient presented with right renal mass. Gross examination of the partial nephrectomy specimen revealed a 2.0 cm red-brown hemorrhagic and cystic mass.
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Case History: A 58-year-old female patient presented with right renal mass. Gross examination of the partial nephrectomy specimen revealed a 2.0 cm red-brown hemorrhagic and cystic mass.
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